Lecture 93: Methods and Approaches in Identification of genes for Human Genetic Disorders

When: Thursday April 14, 2016 – 7:30 PM
Where: Montgomery Community College (Rockville Campus) – Humanity Building (HU), Conference Room 009 (Get Directions, Campus Map )

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Speaker: Abbas Parsian, Ph.D.
Language: Farsi

Synopsis:

The advancements in biotechnology especially as related to DNA have made gene identification of human genetic disorders more feasible. The main goals of these methods are to develop tools for early diagnosis, prognosis, new drug and treatment development and family counseling. In this type of research, the first step is to determine whether a disorder is inherited from parents to their children. The major methods of gene identification are linkage analysis meaning tracking the transmission of a marker with a disorder from one generation to the next. The second method is association analysis by comparing the frequency of a marker in a group of patients to healthy individuals. The third method is the development of an animal model for a disorder and the identification of the gene in the model organism; then, identifying the same gene in human. After the identification of a linked marker(s) to a disorder, it is necessary to look for genes in the genomic region where the maker is located. The next step is sequencing of the candidate genes and looking for mutations. Any gene that harbors a mutation(s) will be the gene for the disorder of interest. Today, with the advancements in nanotechnology we can screen hundreds of mutations for many disorders at the same time.

About the Speaker:

Dr. Parsian received his doctoral degree in Human Genetics from Michigan State University with emphasis on Pediatric Neurology and Mental retardation disorders. To advance his research training in gene identification of complex human genetic disorders, he did two years of post-doctoral work at Washington University School of Medicine where he was offered faculty position in the departments of Psychiatry and Neurology. During his tenure at WashU School of Medicine, Dr. Parsian established and directed DNA Core facility as part of NIMH/NIH Center grant funds. At the same time he became the director of Human DNA Polymorphism laboratory. In addition, he started several large, national and international gene identification projects including Parkinson’s disease, Birth defects due to consanguinity and animal models of complex genetic disorders. Also, he developed several methodological and analytical strategies to identify human genetic variations and disorder genes. Then, he moved to University of Arkansas for Medical Sciences as professor of Human Genetics and Pediatrics where he directed the Human Genomics Center and Laboratory of Neurogenetics. On January 2009, Dr. Parsian accepted a position of investigator and Project Scientist at NIAAA/NIH. Dr. Parsian have received many NIH grants and awards for his research accomplishments.

For this lecture: light refreshment will be provided

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Lecture 92: Is your mouth the gateway to your body?

When: Thursday March 10, 2016 – 7:30 PM
Where: Montgomery Community College (Rockville Campus) – Humanity Building (HU), Conference Room 009 (Get Directions, Campus Map )

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Speaker: Ahmad Soolari, DMD, MS
Language: English

Synopsis:

Maintaining good oral health habits now is especially important because unhealthy bacteria in the mouth not only can harm your teeth and gums but may be associated with serious medical conditions. Research has shown that infections in the mouth may be associated with heart disease, stroke, diabetes, pneumonia and other health problems that are common in older adults. It really only takes a few simple steps, brushing and flossing daily, visiting your dentist regularly and eating nutritious foods to be Mouth Healthy for Life (References: American Dental Association).
You should plan to attend the presentation if you are

  • Adult and having gum disease, tooth pain, dry mouth, cavity, missing teeth, sensitive teeth, infected teeth, lose teeth, receding gums, bleeding gums, broken down teeth, overlapping teeth, teeth with root canal problems, difficulty with chewing foods, difficulty swallowing, difficulty pronouncing words (speech problems), bite problems, snoring, dental anxiety, unhappy with your crowns or dentures, and unhappy with your smile.
  • Having medical conditions such as diabetes, asthma, depression/ anxiety, cancer, pregnancy (pregnant or planning to be), cardiovascular disease, osteoporosis, dry mouth, bad breath, sleep apnea, and taking medications for your medical conditions.
  • Concern with your children/ toddler/ teenagers or young adults with oral health problems
  • Suffering from oral lesions (ulcerations) such as Herpes or Aphthous
  • Interested in having healthy habits that maintain your oral health in optimum conditions
  • Concern about mental health and its impact on oral health
    Please visit www.drsoolari.com for more information.

About the Speaker:

Dr. Soolari earned his doctorate from the University Of Mississippi Medical Center School Of Dentistry in 1990, where he received several academic awards. He received his specialty postdoc training in periodontics from the Eastman Dental and Master of Science degree from the University of Rochester, Rochester, New York. He achieved the distinction of Diplomate of the American Board of Periodontology in 1997.

  • Diplomate and Examiner of the American Board of Periodontology
  • Practitioner-Investigator with the NDPBRN (National Dental Practitioner-Based Research Network), conducted by the University of Rochester, Rochester NY
  • Editorial Board of Journal of Clinical Advances in Periodontics, Journal of the International Academy of Periodontology (JIAP), Medical Science Monitor (MSM) and the Journal of Implant and Advance Clinical Dentistry

For this lecture: light refreshment will be provided

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Lecture 91: Evidence Based Design: An Interdisciplinary Design Approach to Improve Health and Well-Being

When: Thursday February 11, 2016 – 7:30 PM
Where: Montgomery Community College (Rockville Campus) – Humanity Building (HU), Conference Room 009 (Get Directions, Campus Map )

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Speaker: Hessam Ghamari, Ph.D.
Language: Farsi






Synopsis:

Evidence-Based Design (EBD) is the process of basing decisions about the built environment on credible research to achieve the best possible outcomes. EBD has become popular in the field of healthcare design to improve healing process through increasing safety, fostering patient and staff well being, and reducing length of stay and stress. EBD is an approach used by interior designers, architects, facility managers, and healthcare administrators in the planning, design, and construction of commercial buildings. After three decades of research, there is enough evidence that different health outcomes are directly or indirectly related to some design decisions. Although extensive studies have been devoted to EBD, less attention has been paid to identifying the relationships between specific design interventions and their implications for healthcare outcomes. This talk consists of the EBD introduction and three empirical research projects that relate to the design interventions and their implications. The first project studies the neural responses of human brain when exposed to photographic sky compositions. The second study explores neural activation in adult brains in response to visual stimulus containing formal environmental attributes, and the last study examines eye-fixations during navigation in unfamiliar environments to identify visual environmental elements and attributes of wayfinding.

About the Speaker:

Dr. Hessam Ghamari is an assistant professor in Interior Design program at Appalachian State University. Dr. Ghamari received his PhD in Environmental Interior Design from Texas Tech University (TTU), and has over 10 years’ experience in research, practice, and teaching in interior design and architecture in the United States and Iran. He also earned his M.Sc. degree in interior design from Texas Tech University and M.Arch degree from Iran Science and Technology University (IUST). His research efforts have been recognized by several awards throughout his academic career including “Best Student of The Year” in the college of Human Sciences at TTU, “Winner of Covenant Health and Social Services Fellowship”, “EDRAIT of the month (June 2015) by Environmental Design Research Association (EDRA)”, and “Best Researcher” in the school of Architecture and Environment Design at IUST. His primary research interests lie with evidence based healthcare design, wayfinding in unfamiliar environments, sustainable architecture, neuroscience and architecture, and cultural approaches in design. Dr. Ghamari has also been involved in funded research projects in various areas of neuroscience and architecture and environmental design. He has published numerous articles in peer-reviewed journals and international conferences on environment psychology, evidence based design, and healthcare design.

For this lecture: light refreshment will be provided

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